How to synthesize SIMbiont in Quarantine in Marathon – Parasitism 5 guide

The Parasitism 5 contract is a priority task to complete for the Sekiguchi faction in Marathon, and it's a collection of three different activities. Parasitism 5 is the final contract in the series, and this guide will help you complete all three tasks.Table of contentsMarathon Parasitism 5 contract walkthroughHow to extract biotic sample from Sparkleaf in Bio-ResearchHow to synthesize SIMbiont in Quarantine and inject yourselfMarathon Parasitism 5 contract walkthrough The Parasitism 5 contract can be broken down into three tasks.Extract biotic sample from Sparkleaf in Bio-ResearchSynthesize SIMbiont in Quarantine and inject yourselfAllow the SIMbiont to integrate with your shell; then exfilHow to extract biotic sample from Sparkleaf in Bio-Research For the first task, head to the Bio-Research location in the northern area of the map. You'll first need to pick up Sparkleaf that can grow among vegetation. Image via Bungie They don't have a specific location, but they're fairly common. Once you find a Sparkleaf, head to the marked location in the image below. Screenshot and remix by Destructoid You'll find an extraction machine to extract a biotic sample from the Sparkleaf (place it in its inventory and then wait for a few seconds). Image via Bungie How to synthesize SIMbiont in Quarantine and inject yourself Screenshot and remix by Destructoid Pick up the sample and head to the southwest part of the map, where you'll find the Quarantine POI. I have marked the location where you'll find a small room with the terminal inside (will be highlighted by a quest marker when you're at the marked spot). Image via Bungie Access the Synthesizer and place the sample to get the SIMbiont. Inject yourself with the item and then wait for 1 minute and 30 seconds. You'll need to survive a UESC onslaught as the SIMbiont integrates with your shell. Once you manage to survive the 90 seconds, safely exfil from the map, and you'll complete the final Parasitism contract in Marathon. The post How to synthesize SIMbiont in Quarantine in Marathon – Parasitism 5 guide appeared first on Destructoid.

Mar 9, 2026 - 07:25

How to synthesize SIMbiont in Quarantine in Marathon – Parasitism 5 guide

The Parasitism 5 contract is a priority task to complete for the Sekiguchi faction in Marathon, and it's a collection of three different activities.

Parasitism 5 is the final contract in the series, and this guide will help you complete all three tasks.

Table of contents

Marathon Parasitism 5 contract walkthrough
- How to extract biotic sample from Sparkleaf in Bio-Research
- How to synthesize SIMbiont in Quarantine and inject yourself

Marathon Parasitism 5 contract walkthrough

The Parasitism 5 contract can be broken down into three tasks.

Extract biotic sample from Sparkleaf in Bio-Research
Synthesize SIMbiont in Quarantine and inject yourself
Allow the SIMbiont to integrate with your shell; then exfil

How to extract biotic sample from Sparkleaf in Bio-Research

For the first task, head to the Bio-Research location in the northern area of the map. You'll first need to pick up Sparkleaf that can grow among vegetation.

Image via Bungie They don't have a specific location, but they're fairly common. Once you find a Sparkleaf, head to the marked location in the image below.

Screenshot and remix by Destructoid You'll find an extraction machine to extract a biotic sample from the Sparkleaf (place it in its inventory and then wait for a few seconds).

Image via Bungie

How to synthesize SIMbiont in Quarantine and inject yourself

Screenshot and remix by Destructoid Pick up the sample and head to the southwest part of the map, where you'll find the Quarantine POI. I have marked the location where you'll find a small room with the terminal inside (will be highlighted by a quest marker when you're at the marked spot).

Image via Bungie Access the Synthesizer and place the sample to get the SIMbiont. Inject yourself with the item and then wait for 1 minute and 30 seconds. You'll need to survive a UESC onslaught as the SIMbiont integrates with your shell. Once you manage to survive the 90 seconds, safely exfil from the map, and you'll complete the final Parasitism contract in Marathon.

The post How to synthesize SIMbiont in Quarantine in Marathon – Parasitism 5 guide appeared first on Destructoid.

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